A surgical approach in the treatment of preputial gland abscesses in mice

BACKGROUND: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition. RESULTS: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were su...

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Autores principales: Bertrand, Henri G. M. J., Thomas, Aurelie A., Ellen, Yvette C., Dorward, Robert S., Flecknell, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717595/
https://www.ncbi.nlm.nih.gov/pubmed/26785639
http://dx.doi.org/10.1186/s12917-016-0636-5
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author Bertrand, Henri G. M. J.
Thomas, Aurelie A.
Ellen, Yvette C.
Dorward, Robert S.
Flecknell, Paul A.
author_facet Bertrand, Henri G. M. J.
Thomas, Aurelie A.
Ellen, Yvette C.
Dorward, Robert S.
Flecknell, Paul A.
author_sort Bertrand, Henri G. M. J.
collection PubMed
description BACKGROUND: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition. RESULTS: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were successfully removed in all of the animals with a low rate of post-surgery complications. Abscess recurrence due to incomplete gland resection occurred in 2.3 % of animals. Surgical wound opening (3.1 %) and infection of the surgical site (2.3 %) also occurred but were treated successfully. CONCLUSION: In the study described here, early intervention was successful in preventing intercurrent infection compromising both animal welfare and the outcome of the study.
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spelling pubmed-47175952016-01-20 A surgical approach in the treatment of preputial gland abscesses in mice Bertrand, Henri G. M. J. Thomas, Aurelie A. Ellen, Yvette C. Dorward, Robert S. Flecknell, Paul A. BMC Vet Res Methodology Article BACKGROUND: Preputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition. RESULTS: Surgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were successfully removed in all of the animals with a low rate of post-surgery complications. Abscess recurrence due to incomplete gland resection occurred in 2.3 % of animals. Surgical wound opening (3.1 %) and infection of the surgical site (2.3 %) also occurred but were treated successfully. CONCLUSION: In the study described here, early intervention was successful in preventing intercurrent infection compromising both animal welfare and the outcome of the study. BioMed Central 2016-01-19 /pmc/articles/PMC4717595/ /pubmed/26785639 http://dx.doi.org/10.1186/s12917-016-0636-5 Text en © Bertrand et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Methodology Article
Bertrand, Henri G. M. J.
Thomas, Aurelie A.
Ellen, Yvette C.
Dorward, Robert S.
Flecknell, Paul A.
A surgical approach in the treatment of preputial gland abscesses in mice
title A surgical approach in the treatment of preputial gland abscesses in mice
title_full A surgical approach in the treatment of preputial gland abscesses in mice
title_fullStr A surgical approach in the treatment of preputial gland abscesses in mice
title_full_unstemmed A surgical approach in the treatment of preputial gland abscesses in mice
title_short A surgical approach in the treatment of preputial gland abscesses in mice
title_sort surgical approach in the treatment of preputial gland abscesses in mice
topic Methodology Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717595/
https://www.ncbi.nlm.nih.gov/pubmed/26785639
http://dx.doi.org/10.1186/s12917-016-0636-5
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