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Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia

BACKGROUND: Microglia recognize pathogen-associated molecular patterns such as double-stranded RNA (dsRNA) present in some viruses. Polyinosinic-polycytidylic acid [poly(I:C)] is a synthetic analog of dsRNA that activates different molecules, such as retinoic acid-inducible gene I, melanoma differen...

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Detalles Bibliográficos
Autores principales:	de Oliveira, Antonio Carlos Pinheiro, Yousif, Nizar M., Bhatia, Harsharan Singh, Hermanek, Julia, Huell, Michael, Fiebich, Bernd L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717620/ https://www.ncbi.nlm.nih.gov/pubmed/26780827 http://dx.doi.org/10.1186/s12974-015-0473-7

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