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A review of ablative techniques in the treatment of breast fibroadenomata

INTRODUCTION: Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomat...

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Autores principales: Peek, Mirjam C. L., Ahmed, Muneer, Pinder, Sarah E., Douek, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717637/
https://www.ncbi.nlm.nih.gov/pubmed/26788322
http://dx.doi.org/10.1186/s40349-016-0045-z
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author Peek, Mirjam C. L.
Ahmed, Muneer
Pinder, Sarah E.
Douek, Michael
author_facet Peek, Mirjam C. L.
Ahmed, Muneer
Pinder, Sarah E.
Douek, Michael
author_sort Peek, Mirjam C. L.
collection PubMed
description INTRODUCTION: Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomatic. For symptomatic patients, the lumps can be surgically excised or removed interventionally by vacuum-assisted mammotomy (VAM). Ablative techniques like high-intensity focused ultrasound (HIFU), cryo-ablation and laser ablation have also been used for the treatment of FAD, providing a minimally invasive treatment without scarring or poor cosmesis. This review summarises current trials using minimally invasive ablative techniques in the treatment of breast FAD. METHODS: A comprehensive review of studies using minimally invasive ablative techniques was performed. RESULTS: There are currently several trials completed or recruiting patients using HIFU, cryo-ablation and laser ablation in the treatment of breast FAD. The results look very promising but cannot be compared at this point due to heterogeneity between studies. CONCLUSION: Minimally invasive ablative techniques like HIFU, cryo-ablation and laser ablation are promising in the treatment of breast FAD. Future trials should be randomised and contain larger numbers of patients to determine the effectiveness of ablative techniques with more precision.
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spelling pubmed-47176372016-01-20 A review of ablative techniques in the treatment of breast fibroadenomata Peek, Mirjam C. L. Ahmed, Muneer Pinder, Sarah E. Douek, Michael J Ther Ultrasound Review INTRODUCTION: Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomatic. For symptomatic patients, the lumps can be surgically excised or removed interventionally by vacuum-assisted mammotomy (VAM). Ablative techniques like high-intensity focused ultrasound (HIFU), cryo-ablation and laser ablation have also been used for the treatment of FAD, providing a minimally invasive treatment without scarring or poor cosmesis. This review summarises current trials using minimally invasive ablative techniques in the treatment of breast FAD. METHODS: A comprehensive review of studies using minimally invasive ablative techniques was performed. RESULTS: There are currently several trials completed or recruiting patients using HIFU, cryo-ablation and laser ablation in the treatment of breast FAD. The results look very promising but cannot be compared at this point due to heterogeneity between studies. CONCLUSION: Minimally invasive ablative techniques like HIFU, cryo-ablation and laser ablation are promising in the treatment of breast FAD. Future trials should be randomised and contain larger numbers of patients to determine the effectiveness of ablative techniques with more precision. BioMed Central 2016-01-19 /pmc/articles/PMC4717637/ /pubmed/26788322 http://dx.doi.org/10.1186/s40349-016-0045-z Text en © Peek et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Peek, Mirjam C. L.
Ahmed, Muneer
Pinder, Sarah E.
Douek, Michael
A review of ablative techniques in the treatment of breast fibroadenomata
title A review of ablative techniques in the treatment of breast fibroadenomata
title_full A review of ablative techniques in the treatment of breast fibroadenomata
title_fullStr A review of ablative techniques in the treatment of breast fibroadenomata
title_full_unstemmed A review of ablative techniques in the treatment of breast fibroadenomata
title_short A review of ablative techniques in the treatment of breast fibroadenomata
title_sort review of ablative techniques in the treatment of breast fibroadenomata
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717637/
https://www.ncbi.nlm.nih.gov/pubmed/26788322
http://dx.doi.org/10.1186/s40349-016-0045-z
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