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PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P(2)‐dependent actin remodeling

Altered abundance of phosphatidyl inositides (PIs) is a feature of cancer. Various PIs mark the identity of diverse membranes in normal and malignant cells. Phosphatidylinositol 4,5‐bisphosphate (PI(4,5)P(2)) resides predominantly in the plasma membrane, where it regulates cellular processes by recr...

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Detalles Bibliográficos
Autores principales:	Sengelaub, Caitlin A, Navrazhina, Kristina, Ross, Jason B, Halberg, Nils, Tavazoie, Sohail F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717998/ https://www.ncbi.nlm.nih.gov/pubmed/26620550 http://dx.doi.org/10.15252/embj.201591973

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