Overexpression of TLR2 and TLR9 on monocyte subsets of active rheumatoid arthritis patients contributes to enhance responsiveness to TLR agonists

BACKGROUND: Synovial infiltration of monocytes is commonly associated with inflammation in rheumatoid arthritis (RA). Toll-like receptors (TLRs) are innate sensors that recognize cell debris and microbial components in host, a process contributing to maintain chronic inflammation in RA. We assessed...

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Detalles Bibliográficos
Autores principales: Lacerte, Patricia, Brunet, Alexandre, Egarnes, Benoit, Duchêne, Benjamin, Brown, Jacques P., Gosselin, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718023/
https://www.ncbi.nlm.nih.gov/pubmed/26759164
http://dx.doi.org/10.1186/s13075-015-0901-1

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