DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system

BACKGROUND: Synovial fibroblasts play a key role in joint destruction and regulation of the inflammatory infiltrate in established rheumatoid arthritis (RA). The mechanisms by which this occurs in the earliest stages of RA are largely unknown. We investigated the role of Dickkopf-related protein 1 (...

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Detalles Bibliográficos
Autores principales: Juarez, Maria, McGettrick, Helen M., Scheel-Toellner, Dagmar, Yeo, Lorraine, Spengler, Julia, de Paz, Banesa, Hardy, Rowan, Cooper, Mark, Raza, Karim, Buckley, Christopher D., Filer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718043/
https://www.ncbi.nlm.nih.gov/pubmed/26782930
http://dx.doi.org/10.1186/s13075-016-0915-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718043/
https://www.ncbi.nlm.nih.gov/pubmed/26782930
http://dx.doi.org/10.1186/s13075-016-0915-3

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