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Physical evidence supporting a ribosomal shunting mechanism of translation initiation for BACE1 mRNA
In Alzheimer disease, elevated levels of the BACE1 enzyme are correlated with increased production of amyloid peptides and disease pathology. The increase in BACE1 levels is post-transcriptional and may involve altered translation efficiency. Earlier studies have indicated that translation of BACE1...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718059/ https://www.ncbi.nlm.nih.gov/pubmed/26824018 http://dx.doi.org/10.4161/trla.24400 |