Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function

In yeast Saccharomyces cerevisiae, 25S rRNA makes up the major mass and shape of the 60S ribosomal subunit. During translation initiation, the 60S subunit joins the 40S initiation complex, producing the 80S initiation complex. During elongation, the 60S subunit binds the CCA-ends of aminoacyl- and p...

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Detalles Bibliográficos
Autores principales: Nemoto, Naoki, Udagawa, Tsuyoshi, Chowdhury, Wasimul, Kitabatake, Makoto, Shin, Byung-shik, Hiraishi, Hiroyuki, Wang, Suzhi, Singh, Chingakham Ranjit, Brown, Susan J., Ohno, Mutsuhito, Asano, Katsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718063/
https://www.ncbi.nlm.nih.gov/pubmed/26824023
http://dx.doi.org/10.4161/trla.26402

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