Cargando…

The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target...

Descripción completa

Detalles Bibliográficos
Autores principales: Alexander, Stephen PH, Peters, John A, Kelly, Eamonn, Marrion, Neil, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718212/
https://www.ncbi.nlm.nih.gov/pubmed/26650440
http://dx.doi.org/10.1111/bph.13350
_version_ 1782410756102291456
author Alexander, Stephen PH
Peters, John A
Kelly, Eamonn
Marrion, Neil
Benson, Helen E
Faccenda, Elena
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
author_facet Alexander, Stephen PH
Peters, John A
Kelly, Eamonn
Marrion, Neil
Benson, Helen E
Faccenda, Elena
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
author_sort Alexander, Stephen PH
collection PubMed
description The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13349/full. Ligand‐gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and GRAC and provides a permanent, citable, point‐in‐time record that will survive database updates.
format Online
Article
Text
id pubmed-4718212
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-47182122016-11-28 The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels Alexander, Stephen PH Peters, John A Kelly, Eamonn Marrion, Neil Benson, Helen E Faccenda, Elena Pawson, Adam J Sharman, Joanna L Southan, Christopher Davies, Jamie A Br J Pharmacol The Concise Guide to PHARMACOLOGY 2015/16 The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13349/full. Ligand‐gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and GRAC and provides a permanent, citable, point‐in‐time record that will survive database updates. John Wiley and Sons Inc. 2015-12 2015-12-09 /pmc/articles/PMC4718212/ /pubmed/26650440 http://dx.doi.org/10.1111/bph.13350 Text en © 2015 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle The Concise Guide to PHARMACOLOGY 2015/16
Alexander, Stephen PH
Peters, John A
Kelly, Eamonn
Marrion, Neil
Benson, Helen E
Faccenda, Elena
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title_full The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title_fullStr The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title_full_unstemmed The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title_short The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
title_sort concise guide to pharmacology 2015/16: ligand‐gated ion channels
topic The Concise Guide to PHARMACOLOGY 2015/16
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718212/
https://www.ncbi.nlm.nih.gov/pubmed/26650440
http://dx.doi.org/10.1111/bph.13350
work_keys_str_mv AT alexanderstephenph theconciseguidetopharmacology201516ligandgatedionchannels
AT petersjohna theconciseguidetopharmacology201516ligandgatedionchannels
AT kellyeamonn theconciseguidetopharmacology201516ligandgatedionchannels
AT marrionneil theconciseguidetopharmacology201516ligandgatedionchannels
AT bensonhelene theconciseguidetopharmacology201516ligandgatedionchannels
AT faccendaelena theconciseguidetopharmacology201516ligandgatedionchannels
AT pawsonadamj theconciseguidetopharmacology201516ligandgatedionchannels
AT sharmanjoannal theconciseguidetopharmacology201516ligandgatedionchannels
AT southanchristopher theconciseguidetopharmacology201516ligandgatedionchannels
AT daviesjamiea theconciseguidetopharmacology201516ligandgatedionchannels
AT theconciseguidetopharmacology201516ligandgatedionchannels
AT alexanderstephenph conciseguidetopharmacology201516ligandgatedionchannels
AT petersjohna conciseguidetopharmacology201516ligandgatedionchannels
AT kellyeamonn conciseguidetopharmacology201516ligandgatedionchannels
AT marrionneil conciseguidetopharmacology201516ligandgatedionchannels
AT bensonhelene conciseguidetopharmacology201516ligandgatedionchannels
AT faccendaelena conciseguidetopharmacology201516ligandgatedionchannels
AT pawsonadamj conciseguidetopharmacology201516ligandgatedionchannels
AT sharmanjoannal conciseguidetopharmacology201516ligandgatedionchannels
AT southanchristopher conciseguidetopharmacology201516ligandgatedionchannels
AT daviesjamiea conciseguidetopharmacology201516ligandgatedionchannels
AT conciseguidetopharmacology201516ligandgatedionchannels