Risks of Adverse Events Following Coprescription of Statins and Calcium Channel Blockers: A Nationwide Population-Based Study

Some statins (simvastatin, lovastatin, and atorvastatin) are metabolized by cytochrome P450s 3A4 (CYP3A4). Inhibitors of CYP3A4 including some calcium channel blockers (CCBs) might increase statin blood concentration, owing to drug–drug interactions. Risk of adverse events such as acute kidney injur...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Chun, Hsieh, Tsung-Cheng, Chou, Chu-Lin, Wu, Jung-Lun, Fang, Te-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
4200
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718284/
https://www.ncbi.nlm.nih.gov/pubmed/26765458
http://dx.doi.org/10.1097/MD.0000000000002487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718284/
https://www.ncbi.nlm.nih.gov/pubmed/26765458
http://dx.doi.org/10.1097/MD.0000000000002487

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