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A Method for Extracting the Free Energy Surface and Conformational Dynamics of Fast-Folding Proteins from Single Molecule Photon Trajectories

[Image: see text] Single molecule fluorescence spectroscopy holds the promise of providing direct measurements of protein folding free energy landscapes and conformational motions. However, fulfilling this promise has been prevented by technical limitations, most notably, the difficulty in analyzing...

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Detalles Bibliográficos
Autores principales: Ramanathan, Ravishankar, Muñoz, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718529/
https://www.ncbi.nlm.nih.gov/pubmed/25988351
http://dx.doi.org/10.1021/acs.jpcb.5b03176