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Mycobacterium tuberculosis-Specific IL-21(+)IFN-γ(+)CD4(+) T Cells Are Regulated by IL-12

In the current study of Mycobacterium tuberculosis (MTB)-specific T and B cells, we found that MTB-specific peptides from early secreted antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10) induced the expression of IL-21 predominantly in CD4(+) T cells. A fraction of IL-21-expressin...

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Detalles Bibliográficos
Autores principales:	Li, Li, Jiang, Yuxia, Lao, Suihua, Yang, Binyan, Yu, Sifei, Zhang, Yannan, Wu, Changyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718545/ https://www.ncbi.nlm.nih.gov/pubmed/26785168 http://dx.doi.org/10.1371/journal.pone.0147356

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