The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru

Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA sub...

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Autores principales: Nelson, Martha I., Pollett, Simon, Ghersi, Bruno, Silva, Maria, Simons, Mark P., Icochea, Eliana, Gonzalez, Armando E., Segovia, Karen, Kasper, Matthew R., Montgomery, Joel M., Bausch, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718589/
https://www.ncbi.nlm.nih.gov/pubmed/26784331
http://dx.doi.org/10.1371/journal.pone.0146059
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author Nelson, Martha I.
Pollett, Simon
Ghersi, Bruno
Silva, Maria
Simons, Mark P.
Icochea, Eliana
Gonzalez, Armando E.
Segovia, Karen
Kasper, Matthew R.
Montgomery, Joel M.
Bausch, Daniel G.
author_facet Nelson, Martha I.
Pollett, Simon
Ghersi, Bruno
Silva, Maria
Simons, Mark P.
Icochea, Eliana
Gonzalez, Armando E.
Segovia, Karen
Kasper, Matthew R.
Montgomery, Joel M.
Bausch, Daniel G.
author_sort Nelson, Martha I.
collection PubMed
description Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.
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spelling pubmed-47185892016-01-30 The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru Nelson, Martha I. Pollett, Simon Ghersi, Bruno Silva, Maria Simons, Mark P. Icochea, Eliana Gonzalez, Armando E. Segovia, Karen Kasper, Matthew R. Montgomery, Joel M. Bausch, Daniel G. PLoS One Research Article Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America. Public Library of Science 2016-01-19 /pmc/articles/PMC4718589/ /pubmed/26784331 http://dx.doi.org/10.1371/journal.pone.0146059 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Nelson, Martha I.
Pollett, Simon
Ghersi, Bruno
Silva, Maria
Simons, Mark P.
Icochea, Eliana
Gonzalez, Armando E.
Segovia, Karen
Kasper, Matthew R.
Montgomery, Joel M.
Bausch, Daniel G.
The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title_full The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title_fullStr The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title_full_unstemmed The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title_short The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru
title_sort genetic diversity of influenza a viruses in wild birds in peru
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718589/
https://www.ncbi.nlm.nih.gov/pubmed/26784331
http://dx.doi.org/10.1371/journal.pone.0146059
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