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Molecular Determinants of GS-9620-Dependent TLR7 Activation

GS-9620 is an orally administered agonist of Toll-like receptor (TLR)7 currently being evaluated in clinical studies for the treatment of chronic HBV and HIV patients. GS-9620 has shown antiviral efficacy in preclinical models of chronic hepadnavirus infection in woodchuck as well as chimpanzee. How...

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Detalles Bibliográficos
Autores principales:	Rebbapragada, Indrani, Birkus, Gabriel, Perry, Jason, Xing, Weimei, Kwon, HyockJoo, Pflanz, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718629/ https://www.ncbi.nlm.nih.gov/pubmed/26784926 http://dx.doi.org/10.1371/journal.pone.0146835

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