Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

Phenotyping of Gprc6a KO mice has shown that this promiscuous class C G protein coupled receptor is variously involved in regulation of metabolism, inflammation and endocrine function. Such effects are described as mediated by extracellular calcium, L-amino acids, the bone-derived peptide osteocalci...

Descripción completa

Detalles Bibliográficos
Autores principales: Rueda, Patricia, Harley, Elizabeth, Lu, Yao, Stewart, Gregory D., Fabb, Stewart, Diepenhorst, Natalie, Cremers, Béatrice, Rouillon, Marie-Hélène, Wehrle, Isabelle, Geant, Anne, Lamarche, Gwladys, Leach, Katie, Charman, William N., Christopoulos, Arthur, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718634/
https://www.ncbi.nlm.nih.gov/pubmed/26785252
http://dx.doi.org/10.1371/journal.pone.0146846

Ejemplares similares

Ejemplares similares