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Cell and Microvesicle Urine microRNA Deep Sequencing Profiles from Healthy Individuals: Observations with Potential Impact on Biomarker Studies
BACKGROUND: Urine is a potential source of biomarkers for diseases of the kidneys and urinary tract. RNA, including microRNA, is present in the urine enclosed in detached cells or in extracellular vesicles (EVs) or bound and protected by extracellular proteins. Detection of cell- and disease-specifi...
Autores principales: | Ben-Dov, Iddo Z., Whalen, Veronica M., Goilav, Beatrice, Max, Klaas E. A., Tuschl, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718679/ https://www.ncbi.nlm.nih.gov/pubmed/26785265 http://dx.doi.org/10.1371/journal.pone.0147249 |
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