Cargando…

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

Our understanding of the antigen presentation pathway has recently been enhanced with the identification that the tapasin-related protein TAPBPR is a second major histocompatibility complex (MHC) class I-specific chaperone. We sought to determine whether, like tapasin, TAPBPR can also influence MHC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hermann, Clemens, van Hateren, Andy, Trautwein, Nico, Neerincx, Andreas, Duriez, Patrick J, Stevanović, Stefan, Trowsdale, John, Deane, Janet E, Elliott, Tim, Boyle, Louise H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718805/ https://www.ncbi.nlm.nih.gov/pubmed/26439010 http://dx.doi.org/10.7554/eLife.09617

Ejemplares similares

TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway
por: Neerincx, Andreas, et al.
Publicado: (2017)

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever
por: Ilca, F Tudor, et al.
Publicado: (2018)

Preferential interaction of MHC class I with TAPBPR in the absence of glycosylation
por: Neerincx, Andreas, et al.
Publicado: (2019)

TAPBPR isoforms exhibit altered association with MHC class I
por: Porter, Keith M, et al.
Publicado: (2014)

Recent advances in Major Histocompatibility Complex (MHC) class I antigen presentation: Plastic MHC molecules and TAPBPR-mediated quality control
por: van Hateren, Andy, et al.
Publicado: (2017)

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle
por: McShan, Andrew C., et al.
Publicado: (2018)

The glycosylation status of MHC class I molecules impacts their interactions with TAPBPR
por: Ilca, F. Tudor, et al.
Publicado: (2021)

Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR
por: Ilca, F. Tudor, et al.
Publicado: (2019)

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap
por: McShan, Andrew C., et al.
Publicado: (2021)

The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I
por: Sagert, Lina, et al.
Publicado: (2023)

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor
por: Sagert, Lina, et al.
Publicado: (2020)

Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond
por: Margulies, David H., et al.
Publicado: (2023)

A Missing Switch in Peptide Exchange for MHC Class II Molecules
por: Freund, Christian, et al.
Publicado: (2019)

Rapid peptide exchange on MHC class I by small molecules elucidates dynamics of bound peptide
por: Hadeler, Andries, et al.
Publicado: (2022)

Peptide binding characteristics of the non-classical class Ib MHC molecule HLA-E assessed by a recombinant random peptide approach
por: Stevens, James, et al.
Publicado: (2001)

A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization
por: Dalchau, Neil, et al.
Publicado: (2011)

Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function
por: van Hateren, Andy, et al.
Publicado: (2015)

MHC class II complexes sample intermediate states along the peptide exchange pathway
por: Wieczorek, Marek, et al.
Publicado: (2016)

Anchor Side Chains of Short Peptide Fragments Trigger Ligand-Exchange of Class II MHC Molecules
por: Gupta, Shashank, et al.
Publicado: (2008)

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility
por: Ayres, Cory M., et al.
Publicado: (2019)

The MHC class I peptide repertoire is molded by the transcriptome
por: Fortier, Marie-Hélène, et al.
Publicado: (2008)

Motifs and supermotifs for MHC class II binding peptides
Publicado: (1995)

Production and Thermal Exchange of Conditional Peptide‐MHC I Multimers
por: Luimstra, Jolien J., et al.
Publicado: (2019)

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding
por: Chappell, Paul E, et al.
Publicado: (2015)

Model for the Peptide-Free Conformation of Class II MHC Proteins
por: Painter, Corrie A., et al.
Publicado: (2008)

Non-conventional sources of peptides presented by MHC class I
por: Starck, Shelley R., et al.
Publicado: (2011)

Prediction of MHC class I binding peptides, using SVMHC
por: Dönnes, Pierre, et al.
Publicado: (2002)

Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination
por: Cho, Kyung-Jin, et al.
Publicado: (2013)

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity
por: Calis, Jorg J. A., et al.
Publicado: (2013)

CD8(+) T-cell cross-competition is governed by peptide–MHC class I stability
por: Galea, Ian, et al.
Publicado: (2012)

The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV)
por: Butter, Colin, et al.
Publicado: (2013)

Kinetics of Abacavir-Induced Remodelling of the Major Histocompatibility Complex Class I Peptide Repertoire
por: Illing, Patricia T., et al.
Publicado: (2021)

Improving peptide-MHC class I binding prediction for unbalanced datasets
por: Sales, Ana Paula, et al.
Publicado: (2008)

Identical peptides recognized by MHC class I- and II-restricted T cells
Publicado: (1989)

Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes
Publicado: (1989)

ER stress affects processing of MHC class I-associated peptides
por: Granados, Diana P, et al.
Publicado: (2009)

Design of Peptide Immunotherapies for MHC Class-II-Associated Autoimmune Disorders
por: Fridkis-Hareli, Masha
Publicado: (2013)

The Utility of Supertype Clustering in Prediction for Class II MHC-Peptide Binding
por: Shen, Wen-Jun, et al.
Publicado: (2018)

CapsNet-MHC predicts peptide-MHC class I binding based on capsule neural networks
por: Kalemati, Mahmood, et al.
Publicado: (2023)

Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection
por: Anjanappa, Raghavendra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m3q2r0e9lrmc37md8q5gt33r30