pp32 and APRIL are host cell-derived regulators of influenza virus RNA synthesis from cRNA

Replication of influenza viral genomic RNA (vRNA) is catalyzed by viral RNA-dependent RNA polymerase (vRdRP). Complementary RNA (cRNA) is first copied from vRNA, and progeny vRNAs are then amplified from the cRNA. Although vRdRP and viral RNA are minimal requirements, efficient cell-free replication...

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Detalles Bibliográficos
Autores principales: Sugiyama, Kenji, Kawaguchi, Atsushi, Okuwaki, Mitsuru, Nagata, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718810/
https://www.ncbi.nlm.nih.gov/pubmed/26512887
http://dx.doi.org/10.7554/eLife.08939

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