Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model

Group 1 CD1 molecules, CD1a, CD1b and CD1c, present lipid antigens from Mycobacterium tuberculosis (Mtb) to T cells. Mtb lipid-specific group 1 CD1-restricted T cells have been detected in Mtb-infected individuals. However, their role in protective immunity against Mtb remains unclear due to the abs...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Siddiqui, Sarah, Shang, Shaobin, Bian, Yao, Bagchi, Sreya, He, Ying, Wang, Chyung-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718816/
https://www.ncbi.nlm.nih.gov/pubmed/26652001
http://dx.doi.org/10.7554/eLife.08525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718816/
https://www.ncbi.nlm.nih.gov/pubmed/26652001
http://dx.doi.org/10.7554/eLife.08525

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