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Group 3 innate lymphoid cells continuously require the transcription factor GATA3 after commitment

The transcription factor GATA3 is indispensable for the development of all interleukin-7 receptor α (IL-7Rα)-expressing innate lymphoid cells (ILCs). However, the functional role of low GATA3 expression in committed ILC3s has not been identified. We report that GATA3 regulates homeostasis of ILC3s b...

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Detalles Bibliográficos
Autores principales: Zhong, Chao, Cui, Kairong, Wilhelm, Christoph, Hu, Gangqing, Mao, Kairui, Belkaid, Yasmine, Zhao, Keji, Zhu, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718889/
https://www.ncbi.nlm.nih.gov/pubmed/26595886
http://dx.doi.org/10.1038/ni.3318