Cargando…
Group 3 innate lymphoid cells continuously require the transcription factor GATA3 after commitment
The transcription factor GATA3 is indispensable for the development of all interleukin-7 receptor α (IL-7Rα)-expressing innate lymphoid cells (ILCs). However, the functional role of low GATA3 expression in committed ILC3s has not been identified. We report that GATA3 regulates homeostasis of ILC3s b...
Autores principales: | Zhong, Chao, Cui, Kairong, Wilhelm, Christoph, Hu, Gangqing, Mao, Kairui, Belkaid, Yasmine, Zhao, Keji, Zhu, Jinfang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718889/ https://www.ncbi.nlm.nih.gov/pubmed/26595886 http://dx.doi.org/10.1038/ni.3318 |
Ejemplares similares
-
GATA3 Regulates the Development and Functions of Innate Lymphoid Cell Subsets at Multiple Stages
por: Zhu, Jinfang
Publicado: (2017) -
Distinct requirements for T-bet in gut innate lymphoid cells
por: Sciumé, Giuseppe, et al.
Publicado: (2012) -
Gata3 drives development of RORγt(+) group 3 innate lymphoid cells
por: Serafini, Nicolas, et al.
Publicado: (2014) -
GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression
por: Butcher, Matthew J., et al.
Publicado: (2023) -
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation
por: Fang, Difeng, et al.
Publicado: (2018)