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Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

Proteases are important for regulating multiple tumorigenic processes, including angiogenesis, tumor growth, and invasion. Elevated protease expression is associated with poor patient prognosis across numerous tumor types. Several multigene protease families have been implicated in cancer, including...

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Detalles Bibliográficos
Autores principales: Akkari, Leila, Gocheva, Vasilena, Quick, Marsha L., Kester, Jemila C., Spencer, Alison K., Garfall, Alfred L., Bowman, Robert L., Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719311/
https://www.ncbi.nlm.nih.gov/pubmed/26773004
http://dx.doi.org/10.1101/gad.270439.115

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