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Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization
The two major isoforms of the paired-related homeodomain transcription factor 1 (Prrx1), Prrx1a and Prrx1b, are involved in pancreatic development, pancreatitis, and carcinogenesis, although the biological role that these isoforms serve in the systemic dissemination of pancreatic ductal adenocarcino...
Autores principales: | Takano, Shigetsugu, Reichert, Maximilian, Bakir, Basil, Das, Koushik K., Nishida, Takahiro, Miyazaki, Masaru, Heeg, Steffen, Collins, Meredith A., Marchand, Benoît, Hicks, Philip D., Maitra, Anirban, Rustgi, Anil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719312/ https://www.ncbi.nlm.nih.gov/pubmed/26773005 http://dx.doi.org/10.1101/gad.263327.115 |
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