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Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease

BACKGROUND: Alzheimer’s disease affects ~13 % of people in the United States 65 years and older, making it the most common neurodegenerative disorder. Recent work has identified roles for environmental, genetic, and epigenetic factors in Alzheimer’s disease risk. METHODS: We performed a genome-wide...

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Detalles Bibliográficos
Autores principales: Watson, Corey T., Roussos, Panos, Garg, Paras, Ho, Daniel J., Azam, Nidha, Katsel, Pavel L., Haroutunian, Vahram, Sharp, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719699/
https://www.ncbi.nlm.nih.gov/pubmed/26803900
http://dx.doi.org/10.1186/s13073-015-0258-8