Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function

BACKGROUND: Endothelial dysfunction is considered an early step of atherosclerotic vascular disease. Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase (NOS), plays a critical role in the process of atherosclerosis in a uremic environment. Increased plasma ADM...

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Detalles Bibliográficos
Autores principales: Marrocos, Mauro Sergio Martins, Teixeira, Andrei Alkmin, Quinto, Beata Marie, Carmona, Silmara de Melo, Kuniyoshi, Mariana, Rodrigues, Cassio Jose, Dalboni, Maria Aparecida, Manfredi, Silvia, Canziani, Maria Eugênia, Batista, Marcelo Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719742/
https://www.ncbi.nlm.nih.gov/pubmed/26790728
http://dx.doi.org/10.1186/s12944-016-0182-y

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