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Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques
Advancement in microelectromechanical system has facilitated the microfabrication of polymeric substrates and the development of the novel class of controlled drug delivery devices. These vehicles have specifically tailored three dimensional physical and chemical features which together, provide the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719786/ https://www.ncbi.nlm.nih.gov/pubmed/26903763 http://dx.doi.org/10.1016/j.jsps.2013.12.003 |
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author | Jivani, Rishad R. Lakhtaria, Gaurang J. Patadiya, Dhaval D. Patel, Laxman D. Jivani, Nurrudin P. Jhala, Bhagyesh P. |
author_facet | Jivani, Rishad R. Lakhtaria, Gaurang J. Patadiya, Dhaval D. Patel, Laxman D. Jivani, Nurrudin P. Jhala, Bhagyesh P. |
author_sort | Jivani, Rishad R. |
collection | PubMed |
description | Advancement in microelectromechanical system has facilitated the microfabrication of polymeric substrates and the development of the novel class of controlled drug delivery devices. These vehicles have specifically tailored three dimensional physical and chemical features which together, provide the capacity to target cell, stimulate unidirectional controlled release of therapeutics and augment permeation across the barriers. Apart from drug delivery devices microfabrication technology’s offer exciting prospects to generate biomimetic gastrointestinal tract models. BioMEMS are capable of analysing biochemical liquid sample like solution of metabolites, macromolecules, proteins, nucleic acid, cells and viruses. This review summarized multidisciplinary application of biomedical microelectromechanical systems in drug delivery and its potential in analytical procedures. |
format | Online Article Text |
id | pubmed-4719786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-47197862016-02-22 Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques Jivani, Rishad R. Lakhtaria, Gaurang J. Patadiya, Dhaval D. Patel, Laxman D. Jivani, Nurrudin P. Jhala, Bhagyesh P. Saudi Pharm J Review Advancement in microelectromechanical system has facilitated the microfabrication of polymeric substrates and the development of the novel class of controlled drug delivery devices. These vehicles have specifically tailored three dimensional physical and chemical features which together, provide the capacity to target cell, stimulate unidirectional controlled release of therapeutics and augment permeation across the barriers. Apart from drug delivery devices microfabrication technology’s offer exciting prospects to generate biomimetic gastrointestinal tract models. BioMEMS are capable of analysing biochemical liquid sample like solution of metabolites, macromolecules, proteins, nucleic acid, cells and viruses. This review summarized multidisciplinary application of biomedical microelectromechanical systems in drug delivery and its potential in analytical procedures. Elsevier 2016-01 2013-12-23 /pmc/articles/PMC4719786/ /pubmed/26903763 http://dx.doi.org/10.1016/j.jsps.2013.12.003 Text en © 2013 King Saud University. Production and hosting by Elsevier B.V. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Review Jivani, Rishad R. Lakhtaria, Gaurang J. Patadiya, Dhaval D. Patel, Laxman D. Jivani, Nurrudin P. Jhala, Bhagyesh P. Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title | Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title_full | Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title_fullStr | Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title_full_unstemmed | Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title_short | Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques |
title_sort | biomedical microelectromechanical systems (biomems): revolution in drug delivery and analytical techniques |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719786/ https://www.ncbi.nlm.nih.gov/pubmed/26903763 http://dx.doi.org/10.1016/j.jsps.2013.12.003 |
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