Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one

In the title compound, C(19)H(25)NO(2), the pyrrolidine ring adopts an envelope form, with the spiro C atom as the flap, while the cyclo­hexane ring shows a chair form. A weak intra­molecular C—H⋯O inter­action supports the mol­ecular conformation, generating an S(6) ring motif. In the crystal, pair...

Descripción completa

Detalles Bibliográficos
Autores principales: Oishi, Takeshi, Yamamoto, Shio, Yokoyama, Takashi, Kobayashi, Akihiro, Sato, Takaaki, Chida, Noritaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719830/
https://www.ncbi.nlm.nih.gov/pubmed/26870421
http://dx.doi.org/10.1107/S2056989015021209
_version_ 1782410982835879936
author Oishi, Takeshi
Yamamoto, Shio
Yokoyama, Takashi
Kobayashi, Akihiro
Sato, Takaaki
Chida, Noritaka
author_facet Oishi, Takeshi
Yamamoto, Shio
Yokoyama, Takashi
Kobayashi, Akihiro
Sato, Takaaki
Chida, Noritaka
author_sort Oishi, Takeshi
collection PubMed
description In the title compound, C(19)H(25)NO(2), the pyrrolidine ring adopts an envelope form, with the spiro C atom as the flap, while the cyclo­hexane ring shows a chair form. A weak intra­molecular C—H⋯O inter­action supports the mol­ecular conformation, generating an S(6) ring motif. In the crystal, pairs of C—H⋯O inter­actions connect the mol­ecules into inversion dimers with an R (2) (2)(16) ring motif. The dimers are linked by a second pair of C—H⋯O inter­actions, enclosing an R (4) (2)(12) ring motif, into a tape structure along the b axis.
format Online
Article
Text
id pubmed-4719830
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-47198302016-02-11 Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one Oishi, Takeshi Yamamoto, Shio Yokoyama, Takashi Kobayashi, Akihiro Sato, Takaaki Chida, Noritaka Acta Crystallogr E Crystallogr Commun Research Communications In the title compound, C(19)H(25)NO(2), the pyrrolidine ring adopts an envelope form, with the spiro C atom as the flap, while the cyclo­hexane ring shows a chair form. A weak intra­molecular C—H⋯O inter­action supports the mol­ecular conformation, generating an S(6) ring motif. In the crystal, pairs of C—H⋯O inter­actions connect the mol­ecules into inversion dimers with an R (2) (2)(16) ring motif. The dimers are linked by a second pair of C—H⋯O inter­actions, enclosing an R (4) (2)(12) ring motif, into a tape structure along the b axis. International Union of Crystallography 2015-11-25 /pmc/articles/PMC4719830/ /pubmed/26870421 http://dx.doi.org/10.1107/S2056989015021209 Text en © Oishi et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Oishi, Takeshi
Yamamoto, Shio
Yokoyama, Takashi
Kobayashi, Akihiro
Sato, Takaaki
Chida, Noritaka
Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title_full Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title_fullStr Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title_full_unstemmed Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title_short Crystal structure of (±)-(5SR,6SR)-6-ethenyl-1-[(RS)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
title_sort crystal structure of (±)-(5sr,6sr)-6-ethenyl-1-[(rs)-1-phenyl­eth­oxy]-1-aza­spiro­[4.5]decan-2-one
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719830/
https://www.ncbi.nlm.nih.gov/pubmed/26870421
http://dx.doi.org/10.1107/S2056989015021209
work_keys_str_mv AT oishitakeshi crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one
AT yamamotoshio crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one
AT yokoyamatakashi crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one
AT kobayashiakihiro crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one
AT satotakaaki crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one
AT chidanoritaka crystalstructureof5sr6sr6ethenyl1rs1phenylethoxy1azaspiro45decan2one

Ejemplares similares