Cargando…

Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol

In the title compound, C(22)H(19)ClN(4)O, the quinolinol moiety is almost planar [r.m.s. deviation = 0.012 Å]. There is an intra­molecular O—H⋯N hydrogen bond involving the hy­droxy group and a pyridine N atom forming an S(9) ring motif. The dihedral angles between the planes of the quinolinol moiet...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubono, Koji, Kado, Kimiko, Kashiwagi, Yukiyasu, Tani, Keita, Yokoi, Kunihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719835/
https://www.ncbi.nlm.nih.gov/pubmed/26870426
http://dx.doi.org/10.1107/S2056989015022410
_version_ 1782410983975682048
author Kubono, Koji
Kado, Kimiko
Kashiwagi, Yukiyasu
Tani, Keita
Yokoi, Kunihiko
author_facet Kubono, Koji
Kado, Kimiko
Kashiwagi, Yukiyasu
Tani, Keita
Yokoi, Kunihiko
author_sort Kubono, Koji
collection PubMed
description In the title compound, C(22)H(19)ClN(4)O, the quinolinol moiety is almost planar [r.m.s. deviation = 0.012 Å]. There is an intra­molecular O—H⋯N hydrogen bond involving the hy­droxy group and a pyridine N atom forming an S(9) ring motif. The dihedral angles between the planes of the quinolinol moiety and the pyridine rings are 44.15 (9) and 36.85 (9)°. In the crystal, mol­ecules are linked via C—H⋯O hydrogen bonds forming inversion dimers with an R (4) (4)(10) ring motif. The dimers are linked by C—H⋯N hydrogen bonds, forming ribbons along [01-1]. The ribbons are linked by C—H⋯π and π–π inter­actions [inter-centroid distance = 3.7109 (11) Å], forming layers parallel to (01-1).
format Online
Article
Text
id pubmed-4719835
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-47198352016-02-11 Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol Kubono, Koji Kado, Kimiko Kashiwagi, Yukiyasu Tani, Keita Yokoi, Kunihiko Acta Crystallogr E Crystallogr Commun Research Communications In the title compound, C(22)H(19)ClN(4)O, the quinolinol moiety is almost planar [r.m.s. deviation = 0.012 Å]. There is an intra­molecular O—H⋯N hydrogen bond involving the hy­droxy group and a pyridine N atom forming an S(9) ring motif. The dihedral angles between the planes of the quinolinol moiety and the pyridine rings are 44.15 (9) and 36.85 (9)°. In the crystal, mol­ecules are linked via C—H⋯O hydrogen bonds forming inversion dimers with an R (4) (4)(10) ring motif. The dimers are linked by C—H⋯N hydrogen bonds, forming ribbons along [01-1]. The ribbons are linked by C—H⋯π and π–π inter­actions [inter-centroid distance = 3.7109 (11) Å], forming layers parallel to (01-1). International Union of Crystallography 2015-11-28 /pmc/articles/PMC4719835/ /pubmed/26870426 http://dx.doi.org/10.1107/S2056989015022410 Text en © Kubono et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Kubono, Koji
Kado, Kimiko
Kashiwagi, Yukiyasu
Tani, Keita
Yokoi, Kunihiko
Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title_full Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title_fullStr Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title_full_unstemmed Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title_short Crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
title_sort crystal structure of 7-{[bis­(pyridin-2-ylmeth­yl)amino]­meth­yl}-5-chloro­quinolin-8-ol
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719835/
https://www.ncbi.nlm.nih.gov/pubmed/26870426
http://dx.doi.org/10.1107/S2056989015022410
work_keys_str_mv AT kubonokoji crystalstructureof7bispyridin2ylmethylaminomethyl5chloroquinolin8ol
AT kadokimiko crystalstructureof7bispyridin2ylmethylaminomethyl5chloroquinolin8ol
AT kashiwagiyukiyasu crystalstructureof7bispyridin2ylmethylaminomethyl5chloroquinolin8ol
AT tanikeita crystalstructureof7bispyridin2ylmethylaminomethyl5chloroquinolin8ol
AT yokoikunihiko crystalstructureof7bispyridin2ylmethylaminomethyl5chloroquinolin8ol