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Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione

In the title compound, C(30)H(23)N(3)O(4), the central 1-methyl­pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-memb...

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Autores principales: Mathusalini, Sadasivam, Viswanathan, Vijayan, Mohan, Palathurai Subramaniam, Lin, Chia-Her, Velmurugan, Devadasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719967/
https://www.ncbi.nlm.nih.gov/pubmed/26870486
http://dx.doi.org/10.1107/S2056989015023026
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author Mathusalini, Sadasivam
Viswanathan, Vijayan
Mohan, Palathurai Subramaniam
Lin, Chia-Her
Velmurugan, Devadasan
author_facet Mathusalini, Sadasivam
Viswanathan, Vijayan
Mohan, Palathurai Subramaniam
Lin, Chia-Her
Velmurugan, Devadasan
author_sort Mathusalini, Sadasivam
collection PubMed
description In the title compound, C(30)H(23)N(3)O(4), the central 1-methyl­pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-membered ring of the indene-1,3-dione moiety has an envelope conformation with the spiro C atom as the flap. The quinoline ring system adopts an almost planar conformation (r.m.s. deviation = 0.04 Å). The mean planes of the indolin-2-one ring system, the indene-1,3-dione ring system and the the quinoline ring system are inclined to the mean plane of the central 1-methyl­pyrrolidine ring by 77.97 (7), 86.98 (7) and 46.58 (6)°, respectively. In the crystal, mol­ecules are linked via N—H⋯N hydrogen bonds, forming chains along the b axis. The chains are linked via a number of C—H⋯O hydrogen bonds, and C—H⋯π and π–π inter­actions [inter-centroid distance = 3.7404 (9) Å], forming a three-dimensional network.
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spelling pubmed-47199672016-02-11 Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione Mathusalini, Sadasivam Viswanathan, Vijayan Mohan, Palathurai Subramaniam Lin, Chia-Her Velmurugan, Devadasan Acta Crystallogr E Crystallogr Commun Data Reports In the title compound, C(30)H(23)N(3)O(4), the central 1-methyl­pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-membered ring of the indene-1,3-dione moiety has an envelope conformation with the spiro C atom as the flap. The quinoline ring system adopts an almost planar conformation (r.m.s. deviation = 0.04 Å). The mean planes of the indolin-2-one ring system, the indene-1,3-dione ring system and the the quinoline ring system are inclined to the mean plane of the central 1-methyl­pyrrolidine ring by 77.97 (7), 86.98 (7) and 46.58 (6)°, respectively. In the crystal, mol­ecules are linked via N—H⋯N hydrogen bonds, forming chains along the b axis. The chains are linked via a number of C—H⋯O hydrogen bonds, and C—H⋯π and π–π inter­actions [inter-centroid distance = 3.7404 (9) Å], forming a three-dimensional network. International Union of Crystallography 2015-12-12 /pmc/articles/PMC4719967/ /pubmed/26870486 http://dx.doi.org/10.1107/S2056989015023026 Text en © Mathusalini et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Mathusalini, Sadasivam
Viswanathan, Vijayan
Mohan, Palathurai Subramaniam
Lin, Chia-Her
Velmurugan, Devadasan
Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title_full Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title_fullStr Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title_full_unstemmed Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title_short Crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
title_sort crystal structure of 4′-(2-meth­oxy­quinolin-3-yl)-1′-methyl­dispiro­[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719967/
https://www.ncbi.nlm.nih.gov/pubmed/26870486
http://dx.doi.org/10.1107/S2056989015023026
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