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Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione
In the title compound, C(30)H(23)N(3)O(4), the central 1-methylpyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-memb...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719967/ https://www.ncbi.nlm.nih.gov/pubmed/26870486 http://dx.doi.org/10.1107/S2056989015023026 |
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author | Mathusalini, Sadasivam Viswanathan, Vijayan Mohan, Palathurai Subramaniam Lin, Chia-Her Velmurugan, Devadasan |
author_facet | Mathusalini, Sadasivam Viswanathan, Vijayan Mohan, Palathurai Subramaniam Lin, Chia-Her Velmurugan, Devadasan |
author_sort | Mathusalini, Sadasivam |
collection | PubMed |
description | In the title compound, C(30)H(23)N(3)O(4), the central 1-methylpyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-membered ring of the indene-1,3-dione moiety has an envelope conformation with the spiro C atom as the flap. The quinoline ring system adopts an almost planar conformation (r.m.s. deviation = 0.04 Å). The mean planes of the indolin-2-one ring system, the indene-1,3-dione ring system and the the quinoline ring system are inclined to the mean plane of the central 1-methylpyrrolidine ring by 77.97 (7), 86.98 (7) and 46.58 (6)°, respectively. In the crystal, molecules are linked via N—H⋯N hydrogen bonds, forming chains along the b axis. The chains are linked via a number of C—H⋯O hydrogen bonds, and C—H⋯π and π–π interactions [inter-centroid distance = 3.7404 (9) Å], forming a three-dimensional network. |
format | Online Article Text |
id | pubmed-4719967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-47199672016-02-11 Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione Mathusalini, Sadasivam Viswanathan, Vijayan Mohan, Palathurai Subramaniam Lin, Chia-Her Velmurugan, Devadasan Acta Crystallogr E Crystallogr Commun Data Reports In the title compound, C(30)H(23)N(3)O(4), the central 1-methylpyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and the carbonyl C atom. The five-membered ring of the indene-1,3-dione moiety has an envelope conformation with the spiro C atom as the flap. The quinoline ring system adopts an almost planar conformation (r.m.s. deviation = 0.04 Å). The mean planes of the indolin-2-one ring system, the indene-1,3-dione ring system and the the quinoline ring system are inclined to the mean plane of the central 1-methylpyrrolidine ring by 77.97 (7), 86.98 (7) and 46.58 (6)°, respectively. In the crystal, molecules are linked via N—H⋯N hydrogen bonds, forming chains along the b axis. The chains are linked via a number of C—H⋯O hydrogen bonds, and C—H⋯π and π–π interactions [inter-centroid distance = 3.7404 (9) Å], forming a three-dimensional network. International Union of Crystallography 2015-12-12 /pmc/articles/PMC4719967/ /pubmed/26870486 http://dx.doi.org/10.1107/S2056989015023026 Text en © Mathusalini et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports Mathusalini, Sadasivam Viswanathan, Vijayan Mohan, Palathurai Subramaniam Lin, Chia-Her Velmurugan, Devadasan Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title | Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title_full | Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title_fullStr | Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title_full_unstemmed | Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title_short | Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
title_sort | crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719967/ https://www.ncbi.nlm.nih.gov/pubmed/26870486 http://dx.doi.org/10.1107/S2056989015023026 |
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