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Epigenetic Aberrations Are Not Specific to Transcription Factor-Mediated Reprogramming
Somatic cells can be reprogrammed to pluripotency using different methods. In comparison with pluripotent cells obtained through somatic nuclear transfer, induced pluripotent stem cells (iPSCs) exhibit a higher number of epigenetic errors. Furthermore, most of these abnormalities have been described...
Autores principales: | Tiemann, Ulf, Wu, Guangming, Marthaler, Adele Gabriele, Schöler, Hans Robert, Tapia, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720011/ https://www.ncbi.nlm.nih.gov/pubmed/26711876 http://dx.doi.org/10.1016/j.stemcr.2015.11.007 |
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