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Epigenetic Aberrations Are Not Specific to Transcription Factor-Mediated Reprogramming

Somatic cells can be reprogrammed to pluripotency using different methods. In comparison with pluripotent cells obtained through somatic nuclear transfer, induced pluripotent stem cells (iPSCs) exhibit a higher number of epigenetic errors. Furthermore, most of these abnormalities have been described...

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Detalles Bibliográficos
Autores principales: Tiemann, Ulf, Wu, Guangming, Marthaler, Adele Gabriele, Schöler, Hans Robert, Tapia, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720011/
https://www.ncbi.nlm.nih.gov/pubmed/26711876
http://dx.doi.org/10.1016/j.stemcr.2015.11.007

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