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Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells

PURPOSE: HM781-36B is a novel and irreversible pan-human epidermal growth factor receptor (HER) inhibitor with TEC cytoplasmic kinase inhibition. The aim of this study is to evaluate the antitumor activity and mechanism of action for HM781-36B in CRC cell lines. MATERIALS AND METHODS: The CRC cell l...

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Detalles Bibliográficos
Autores principales:	Kang, Mi Hyun, Moon, Sung Ung, Sung, Ji Hea, Kim, Jin Won, Lee, Keun Wook, Lee, Hye Seung, Lee, Jong Seok, Kim, Jee Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720083/ https://www.ncbi.nlm.nih.gov/pubmed/25761479 http://dx.doi.org/10.4143/crt.2014.260

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