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Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish
Telomeres shorten with each cell division and telomere dysfunction is a recognized hallmark of aging. Tissue proliferation is expected to dictate the rate at which telomeres shorten. We set out to test whether proliferative tissues age faster than non-proliferative due to telomere shortening during...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720274/ https://www.ncbi.nlm.nih.gov/pubmed/26789415 http://dx.doi.org/10.1371/journal.pgen.1005798 |