Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish

Telomeres shorten with each cell division and telomere dysfunction is a recognized hallmark of aging. Tissue proliferation is expected to dictate the rate at which telomeres shorten. We set out to test whether proliferative tissues age faster than non-proliferative due to telomere shortening during...

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Detalles Bibliográficos
Autores principales: Carneiro, Madalena C., Henriques, Catarina M., Nabais, Joana, Ferreira, Tânia, Carvalho, Tânia, Ferreira, Miguel Godinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720274/
https://www.ncbi.nlm.nih.gov/pubmed/26789415
http://dx.doi.org/10.1371/journal.pgen.1005798

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