Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages

Here, we studied the underlying mechanism of aldosterone (Aldo)-induced vascular endothelial cell damages by focusing on ceramide. We confirmed that Aldo (at nmol/L) inhibited human umbilical vein endothelial cells (HUVEC) survival, and induced considerable cell apoptosis. We propose that ceramide (...

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Detalles Bibliográficos
Autores principales: Zhang, Yumei, Pan, Yu, Bian, Zhixiang, Chen, Peihua, Zhu, Shijian, Gu, Huiyi, Guo, Liping, Hu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720365/
https://www.ncbi.nlm.nih.gov/pubmed/26788916
http://dx.doi.org/10.1371/journal.pone.0146944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720365/
https://www.ncbi.nlm.nih.gov/pubmed/26788916
http://dx.doi.org/10.1371/journal.pone.0146944

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