Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway

NK cells accumulate at the maternal-fetal interface (MFI) and play essential roles in maintaining immune tolerance during pregnancy. The mechanisms that facilitate NK cells tolerance to fetal tissue are largely unknown. T cell Ig and mucin domain-containing protein 3 (Tim-3) is a newly defined molec...

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Detalles Bibliográficos
Autores principales: Sun, Jintang, Yang, Meixiang, Ban, Yanli, Gao, Wenjuan, Song, Bingfeng, Wang, Yang, Zhang, Yun, Shao, Qianqian, Kong, Beihua, Qu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720443/
https://www.ncbi.nlm.nih.gov/pubmed/26789128
http://dx.doi.org/10.1371/journal.pone.0147186

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