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Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice
Uridine is a pyrimidine nucleoside that exerts restorative functions in tissues under stress. Short-term co-administration of uridine with multiple unrelated drugs prevents drug-induced liver lipid accumulation. Uridine has the ability to modulate liver metabolism; however, the precise mechanism has...
Autores principales: | Urasaki, Yasuyo, Pizzorno, Giuseppe, Le, Thuc T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720477/ https://www.ncbi.nlm.nih.gov/pubmed/26789264 http://dx.doi.org/10.1371/journal.pone.0146994 |
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