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Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that catalyze multiple topologically similar membrane-remodeling processes. Although ESCRT-III subunits polymerize into spirals, how individual ESCRT-III subunits are activated and assembled togethe...

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Detalles Bibliográficos
Autores principales: Tang, Shaogeng, Henne, W Mike, Borbat, Peter P, Buchkovich, Nicholas J, Freed, Jack H, Mao, Yuxin, Fromme, J Christopher, Emr, Scott D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720517/
https://www.ncbi.nlm.nih.gov/pubmed/26670543
http://dx.doi.org/10.7554/eLife.12548