New building blocks or dendritic pseudopeptides for metal chelating

Dendritic oligopeptides have been reported as useful building blocks for many interactions. Starting from hydrazine, we described an approach to create new dendritic pseudopeptides linked with biological systems, such as cell membrane, as chelate metal, Ni(2+)-nitrilotriacetic acid moieties which co...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Min, Nicolas, Irène, Baudy-Floc’h, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720618/
https://www.ncbi.nlm.nih.gov/pubmed/26835235
http://dx.doi.org/10.1186/s40064-016-1703-x
Descripción
Sumario:Dendritic oligopeptides have been reported as useful building blocks for many interactions. Starting from hydrazine, we described an approach to create new dendritic pseudopeptides linked with biological systems, such as cell membrane, as chelate metal, Ni(2+)-nitrilotriacetic acid moieties which could target histidine rich peptides or proteins. Depending on the nature of these new chemical recognition units, they could be integrated into a peptide by coupling in C or N-termini. [Figure: see text]

Ejemplares similares