A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation

The citalopram for Alzheimer’s disease trial evaluated citalopram for the management for agitation in Alzheimer’s disease patients. Sparse data was available from this elderly patient population. A nonlinear mixed effects population pharmacokinetic modeling approach was used to describe the pharmaco...

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Detalles Bibliográficos
Autores principales: Akil, Ayman, Bies, Robert R., Pollock, Bruce G., Avramopoulos, Dimitrios, Devanand, D. P., Mintzer, Jacobo E., Porsteinsson, Anton P., Schneider, Lon S., Weintraub, Daniel, Yesavage, Jerome, Shade, David M., Lyketsos, Constantine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720707/
https://www.ncbi.nlm.nih.gov/pubmed/26611790
http://dx.doi.org/10.1007/s10928-015-9457-6

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