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The rs11515 Polymorphism Is More Frequent and Associated With Aggressive Breast Tumors with Increased ANRIL and Decreased p16(INK4a) Expression
Chromosome position 9p21 encodes three-tumor suppressors p16(INK4a), p14(ARF), and p15(INK4b) and the long non-coding RNA ANRIL (antisense non-coding RNA in the INK4 locus). The rs11515 single-nucleotide polymorphism in the p16(INK4a)/p14(ARF) 3′-untranslated region is associated with glioblastoma,...
Autores principales: | Royds, Janice A., Pilbrow, Anna P., Ahn, Antonio, Morrin, Helen R., Frampton, Chris, Russell, I. Alasdair, Moravec, Christine S., Sweet, Wendy E., Tang, W. H. Wilson, Currie, Margaret J., Hung, Noelyn A., Slatter, Tania L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720739/ https://www.ncbi.nlm.nih.gov/pubmed/26835415 http://dx.doi.org/10.3389/fonc.2015.00306 |
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