Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells

Rasfonin is a fungal secondary metabolite with demonstrated antitumor effects. However, the underlying mechanism of the regulatory role in autophagy initiated by rasfonin is largely unknown. Moreover, the function of Akt to positively mediate the induced autophagy remains elusive. In the present stu...

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Detalles Bibliográficos
Autores principales: Lu, Q, Yan, S, Sun, H, Wang, W, Li, Y, Yang, X, Jiang, X, Che, Y, Xi, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720880/
https://www.ncbi.nlm.nih.gov/pubmed/26633711
http://dx.doi.org/10.1038/cddis.2015.344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720880/
https://www.ncbi.nlm.nih.gov/pubmed/26633711
http://dx.doi.org/10.1038/cddis.2015.344

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