Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition

Although cellular prion protein (PrP(c)) has been suggested to have physiological roles in neurogenesis and angiogenesis, the pathophysiological relevance of both processes remain unknown. To elucidate the role of PrP(c) in post-ischemic brain remodeling, we herein exposed PrP(c) wild type (WT), PrP...

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Detalles Bibliográficos
Autores principales: Doeppner, T R, Kaltwasser, B, Schlechter, J, Jaschke, J, Kilic, E, Bähr, M, Hermann, D M, Weise, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720898/
https://www.ncbi.nlm.nih.gov/pubmed/26673668
http://dx.doi.org/10.1038/cddis.2015.365

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