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Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report

Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complicatio...

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Detalles Bibliográficos
Autores principales: VLAHOVIC, A., GAZIKALOVIC, A., ADJIC, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SpA 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720922/
https://www.ncbi.nlm.nih.gov/pubmed/26824921
http://dx.doi.org/10.14639/0392-100X-105513
Descripción
Sumario:Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complications. Bleomycin is an established antineoplastic drug. It can be used as a sclerosing agent in vascular anomalies. We present a child who was unsuccessfully treated with four surgical resections, with peripheral palsy of facial nerve as complication. The lymphatic malformation was successfully treated in our institution with intralesional administration of bleomycin.