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Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report

Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complicatio...

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Autores principales: VLAHOVIC, A., GAZIKALOVIC, A., ADJIC, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SpA 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720922/
https://www.ncbi.nlm.nih.gov/pubmed/26824921
http://dx.doi.org/10.14639/0392-100X-105513
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author VLAHOVIC, A.
GAZIKALOVIC, A.
ADJIC, O.
author_facet VLAHOVIC, A.
GAZIKALOVIC, A.
ADJIC, O.
author_sort VLAHOVIC, A.
collection PubMed
description Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complications. Bleomycin is an established antineoplastic drug. It can be used as a sclerosing agent in vascular anomalies. We present a child who was unsuccessfully treated with four surgical resections, with peripheral palsy of facial nerve as complication. The lymphatic malformation was successfully treated in our institution with intralesional administration of bleomycin.
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spelling pubmed-47209222016-01-29 Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report VLAHOVIC, A. GAZIKALOVIC, A. ADJIC, O. Acta Otorhinolaryngol Ital Case Series and Reports Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complications. Bleomycin is an established antineoplastic drug. It can be used as a sclerosing agent in vascular anomalies. We present a child who was unsuccessfully treated with four surgical resections, with peripheral palsy of facial nerve as complication. The lymphatic malformation was successfully treated in our institution with intralesional administration of bleomycin. Pacini Editore SpA 2015-10 /pmc/articles/PMC4720922/ /pubmed/26824921 http://dx.doi.org/10.14639/0392-100X-105513 Text en © Copyright by Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way. For details, please refer to http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Case Series and Reports
VLAHOVIC, A.
GAZIKALOVIC, A.
ADJIC, O.
Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title_full Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title_fullStr Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title_full_unstemmed Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title_short Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
title_sort bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report
topic Case Series and Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720922/
https://www.ncbi.nlm.nih.gov/pubmed/26824921
http://dx.doi.org/10.14639/0392-100X-105513
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