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Loss of kinesin-14 results in aneuploidy via kinesin-5-dependent microtubule protrusions leading to chromosome cut
Aneuploidy – chromosome instability leading to incorrect chromosome number in dividing cells – can arise from defects in centrosome duplication, bipolar spindle formation, kinetochore-microtubule attachment, chromatid cohesion, mitotic checkpoint monitoring, or cytokinesis. As most tumors show some...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720966/ https://www.ncbi.nlm.nih.gov/pubmed/26031557 http://dx.doi.org/10.1038/ncomms8322 |