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Interleukin-17-producing decidual CD4+ T cells are not deleterious for human pregnancy when they also produce interleukin-4

BACKGROUND: Trophoblast expressing paternal HLA-C antigens resemble a semiallograft, and could be rejected by maternal CD4+ T lymphocytes. We examined the possible role in human pregnancy of Th17 cells, known to be involved in allograft rejection and reported for this reason to be responsible for mi...

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Detalles Bibliográficos
Autores principales: Lombardelli, Letizia, Logiodice, Federica, Aguerre-Girr, Maryse, Kullolli, Ornela, Haller, Herman, Casart, Ysabel, Berrebi, Alain, L’Faqihi-Olive, Fatima-Ezzahra, Duplan, Valérie, Romagnani, Sergio, Maggi, Enrico, Rukavina, Daniel, Le Bouteiller, Philippe, Piccinni, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721137/
https://www.ncbi.nlm.nih.gov/pubmed/26798325
http://dx.doi.org/10.1186/s12948-016-0039-y