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A case of Trientine Overdose
Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721165/ https://www.ncbi.nlm.nih.gov/pubmed/26862278 http://dx.doi.org/10.4103/0971-6580.172262 |
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author | Hashim, Ahmed Parnell, Nick |
author_facet | Hashim, Ahmed Parnell, Nick |
author_sort | Hashim, Ahmed |
collection | PubMed |
description | Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no further clinical sequelae or significant biochemical abnormalities. This case shows that Trientine has a good safety profile and hence could be used as a first line treatment in patients with Wilson's disease who suffer from psychiatric complications and who might be at risk of self-harm. |
format | Online Article Text |
id | pubmed-4721165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-47211652016-02-09 A case of Trientine Overdose Hashim, Ahmed Parnell, Nick Toxicol Int Case Report Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no further clinical sequelae or significant biochemical abnormalities. This case shows that Trientine has a good safety profile and hence could be used as a first line treatment in patients with Wilson's disease who suffer from psychiatric complications and who might be at risk of self-harm. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4721165/ /pubmed/26862278 http://dx.doi.org/10.4103/0971-6580.172262 Text en Copyright: © Toxicology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Hashim, Ahmed Parnell, Nick A case of Trientine Overdose |
title | A case of Trientine Overdose |
title_full | A case of Trientine Overdose |
title_fullStr | A case of Trientine Overdose |
title_full_unstemmed | A case of Trientine Overdose |
title_short | A case of Trientine Overdose |
title_sort | case of trientine overdose |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721165/ https://www.ncbi.nlm.nih.gov/pubmed/26862278 http://dx.doi.org/10.4103/0971-6580.172262 |
work_keys_str_mv | AT hashimahmed acaseoftrientineoverdose AT parnellnick acaseoftrientineoverdose AT hashimahmed caseoftrientineoverdose AT parnellnick caseoftrientineoverdose |