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Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2)

BACKGROUND: Triggering receptor expressed on myeloid cells-2 (TREM2) exerts important functions in the regulation of monocytes, like dendritic cells, osteoclasts, tissue macrophages, and microglia. Mutations in TREM2 are associated with several diseases, including Nasu-Hakola disease, frontotemporal...

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Detalles Bibliográficos
Autores principales:	Glebov, Konstantin, Wunderlich, Patrick, Karaca, Ilker, Walter, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721188/ https://www.ncbi.nlm.nih.gov/pubmed/26792193 http://dx.doi.org/10.1186/s12974-016-0479-9

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