A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides

[Image: see text] A new biaryl monophosphine ligand (AlPhos, L1) allows for the room-temperature Pd-catalyzed fluorination of a variety of activated (hetero)aryl triflates. Furthermore, aryl triflates and bromides that are prone to give mixtures of regioisomeric aryl fluorides with Pd-catalysis can...

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Detalles Bibliográficos
Autores principales: Sather, Aaron C., Lee, Hong Geun, De La Rosa, Valentina Y., Yang, Yang, Müller, Peter, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721526/
https://www.ncbi.nlm.nih.gov/pubmed/26413908
http://dx.doi.org/10.1021/jacs.5b09308

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