Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism

Protein phosphatase 5 (PP5) is an evolutionary conserved serine/threonine phosphatase. Its dephosphorylation activity modulates a diverse set of cellular factors including protein kinases and the microtubule-associated tau protein involved in neurodegenerative disorders. It is auto-regulated by its...

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Detalles Bibliográficos
Autores principales: Haslbeck, Veronika, Drazic, Adrian, Eckl, Julia M., Alte, Ferdinand, Helmuth, Martin, Popowicz, Grzegorz, Schmidt, Werner, Braun, Frank, Weiwad, Matthias, Fischer, Gunter, Gemmecker, Gerd, Sattler, Michael, Striggow, Frank, Groll, Michael, Richter, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721540/
https://www.ncbi.nlm.nih.gov/pubmed/26182372
http://dx.doi.org/10.1042/BSR20150042

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